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Eiji Oki Selected Research

Trifluridine (Viroptic)

1/2020DNA Replication Stress Induced by Trifluridine Determines Tumor Cell Fate According to p53 Status.
1/2020Detection of trifluridine in tumors of patients with metastatic colorectal cancer treated with trifluridine/tipiracil.
1/2019Cytotoxicity of trifluridine correlates with the thymidine kinase 1 expression level.
10/2018Thymidine Kinase 1 Loss Confers Trifluridine Resistance without Affecting 5-Fluorouracil Metabolism and Cytotoxicity.
12/2017Monitoring trifluridine incorporation in the peripheral blood mononuclear cells of colorectal cancer patients under trifluridine/tipiracil medication.

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Eiji Oki Research Topics

Disease

159Neoplasms (Cancer)
08/2022 - 12/2002
79Stomach Neoplasms (Stomach Cancer)
08/2022 - 12/2002
78Colorectal Neoplasms (Colorectal Cancer)
04/2022 - 07/2008
37Neoplasm Metastasis (Metastasis)
08/2022 - 12/2007
28Esophageal Neoplasms (Esophageal Cancer)
12/2020 - 01/2008
25Colonic Neoplasms (Colon Cancer)
10/2022 - 05/2006
24Breast Neoplasms (Breast Cancer)
01/2021 - 01/2006
20Esophageal Squamous Cell Carcinoma
01/2022 - 08/2011
16Adenocarcinoma
01/2022 - 11/2015
13Microsatellite Instability
10/2021 - 09/2009
13Carcinoma (Carcinomatosis)
05/2019 - 09/2005
11Rectal Neoplasms (Rectal Cancer)
11/2021 - 06/2006
11Carcinogenesis
12/2020 - 08/2007
9Lymphatic Metastasis
08/2022 - 05/2013
9Neutropenia
12/2021 - 04/2013
8Aneuploidy (Aneuploid)
06/2017 - 03/2010
7Gastrointestinal Neoplasms (Gastrointestinal Cancer)
12/2020 - 08/2007
7Chromosomal Instability (Chromosome Stability)
12/2020 - 03/2010
5Disease Progression
01/2022 - 11/2013
5Inflammation (Inflammations)
12/2020 - 01/2014
4Squamous Cell Carcinoma (Epidermoid Carcinoma)
02/2021 - 04/2008
4Triple Negative Breast Neoplasms
01/2021 - 12/2010
3Febrile Neutropenia
12/2021 - 07/2014
3Melanoma (Melanoma, Malignant)
07/2020 - 01/2008
3Fatigue
01/2018 - 07/2014
3Fistula
01/2017 - 05/2015
3Anastomotic Leak
12/2016 - 02/2010
3Peritonitis
01/2016 - 09/2013

Drug/Important Bio-Agent (IBA)

35Oxaliplatin (Eloxatin)FDA LinkGeneric
10/2022 - 01/2008
27Biomarkers (Surrogate Marker)IBA
04/2022 - 01/2012
26DNA (Deoxyribonucleic Acid)IBA
06/2021 - 03/2008
22Proteins (Proteins, Gene)FDA Link
08/2021 - 07/2008
21Fluorouracil (Carac)FDA LinkGeneric
10/2022 - 11/2003
21Bevacizumab (Avastin)FDA Link
01/2022 - 05/2013
17Irinotecan (Camptosar)FDA LinkGeneric
12/2021 - 11/2003
13trifluridine tipiracil drug combinationIBA
07/2021 - 04/2015
11ErbB Receptors (EGF Receptor)IBA
01/2022 - 01/2008
10Pharmaceutical PreparationsIBA
06/2021 - 10/2015
9Capecitabine (Xeloda)FDA Link
10/2022 - 04/2013
9LigandsIBA
08/2021 - 07/2005
9Messenger RNA (mRNA)IBA
12/2020 - 05/2008
9Docetaxel (Taxotere)FDA Link
05/2019 - 11/2003
9Biological ProductsIBA
03/2019 - 04/2012
8Immune Checkpoint InhibitorsIBA
01/2022 - 03/2018
7Leucovorin (Folinic Acid)FDA Link
10/2022 - 01/2011
7Circulating Tumor DNAIBA
04/2022 - 01/2017
7Trastuzumab (Herceptin)FDA Link
01/2021 - 06/2006
7Cetuximab (Erbitux)FDA Link
01/2020 - 05/2013
7Indicators and Reagents (Reagents)IBA
01/2017 - 12/2002
5Cisplatin (Platino)FDA LinkGeneric
02/2021 - 01/2017
5regorafenibIBA
06/2020 - 07/2015
5Trifluridine (Viroptic)FDA LinkGeneric
01/2020 - 12/2017
5Hormones (Hormone)IBA
11/2014 - 01/2006
4Calcibiotic Root Canal SealerIBA
01/2022 - 10/2015
4RNA (Ribonucleic Acid)IBA
08/2021 - 12/2002
4Panitumumab (Vectibix)FDA Link
07/2021 - 05/2013
4Epidermal Growth Factor (EGF)IBA
01/2021 - 07/2005
4B7-H1 AntigenIBA
06/2018 - 08/2016
4ParaffinIBA
10/2017 - 01/2016
4NucleotidesIBA
01/2017 - 03/2008
4Progesterone Receptors (Progesterone Receptor)IBA
01/2017 - 03/2007
4Estrogen ReceptorsIBA
01/2017 - 05/2012
4TensinsIBA
01/2015 - 09/2005
4Heparin-binding EGF-like Growth Factor (HB-EGF)IBA
05/2013 - 07/2005
3Cadherins (E-Cadherin)IBA
08/2022 - 08/2015
3VimentinIBA
08/2022 - 12/2016
3Monoclonal AntibodiesIBA
01/2022 - 01/2021
3RamucirumabIBA
01/2022 - 01/2018
3PlatinumIBA
01/2022 - 10/2015
3Tumor Biomarkers (Tumor Markers)IBA
10/2021 - 11/2015
3Oxygen (Dioxygen)IBA
09/2021 - 10/2013
3AntibodiesIBA
06/2021 - 08/2014
3Type I DNA Topoisomerases (Topoisomerase I)IBA
01/2021 - 01/2018
3NivolumabIBA
11/2020 - 01/2019
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
11/2020 - 01/2017
3afliberceptIBA
11/2020 - 03/2019
3C-Reactive ProteinIBA
07/2020 - 12/2018
3NucleosidesIBA
01/2020 - 10/2018
3Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
11/2019 - 01/2018
3human ERBB2 proteinIBA
11/2018 - 01/2016
3Phosphotransferases (Kinase)IBA
01/2018 - 01/2013
3Formaldehyde (Formol)FDA Link
10/2017 - 01/2016

Therapy/Procedure

73Therapeutics
10/2022 - 11/2005
57Drug Therapy (Chemotherapy)
01/2022 - 11/2003
30Gastrectomy
01/2021 - 01/2010
28Esophagectomy
01/2022 - 01/2008
24Adjuvant Chemotherapy
01/2022 - 11/2003
15Neoadjuvant Therapy
01/2022 - 09/2011
12Lymph Node Excision (Lymph Node Dissection)
04/2022 - 04/2008
10Combination Drug Therapy (Combination Chemotherapy)
02/2021 - 04/2006
8Chemoradiotherapy
01/2021 - 11/2011
7Hepatectomy
09/2017 - 04/2011
7Liver Transplantation
08/2014 - 01/2009
6Immunotherapy
01/2022 - 01/2017
5Length of Stay
12/2018 - 05/2014
4Colectomy
04/2021 - 01/2014
4Radiotherapy
01/2021 - 01/2013
4Lasers (Laser)
10/2018 - 10/2013
3Combined Modality Therapy
01/2021 - 12/2013
3Pancreatectomy
05/2019 - 04/2011